Padres vs Giants Series Odds: San Diego, San Francisco Try to Keep Pace with Dodgers

First Meeting of 2022 for NL West Hopefuls

The San Diego Padres have their work cut out for them. Given the Padres vs Giants series odds suggest they’re a +135 underdog in their series against the San Francisco Giants.

The Padres took two out of three at Philadelphia this week in a series that saw nothing but shutouts. Yu Darvish and two relievers made a two-run fourth-inning rally by the Padres, hold up in Thursday’s series finale. San Diego has been operating without manager Bob Melvin, but he’s expected to return from prostate surgery Friday.

The host San Francisco Giants are also coming off a series win after claiming two of three at Coors Field. Reclamation project Jakob Junis is paying huge dividends early on and will get the start for the Giants in the opener.

Game Information

  • Game: Padres (24-14) at Giants (22-15)
  • Location: Oracle Park
  • Day/Time: Friday, 10:15 p.m. ET
  • Television: Bally Sports San Diego, NBC Sports Bay Area, MLB Network

Padres vs Giants Probable Starting Pitchers

  • Friday: Sean Manaea (Padres) vs Jakob Junis (Giants)
  • Saturday: Joe Musgrove (Padres) vs Carlos Rodon (Giants)
  • Sunday: Mike Clevinger (Padres) vs Alex Wood (Giants)

Padres Loving the Road

The Darvish gem helped San Diego improve to 14-7 on the road. Those 14 wins are second only to the Houston Astros (15), and the squad showed no ill effects of playing without Melvin. Take a look at what dictates Padres vs Giants series odds.

“I haven’t felt a lot of stress in the dugout,” interim manager Ryan Christenson said Thursday.

It’s easy to be stress-free when your staff allows just 15 hits and fans 38 in 28 innings over the course of the Philadelphia series. The run left the San Diego rotation with a 3.36 ERA, seventh-lowest in the majors.

It’s usually safe to put some trust in the Padres’ starters when conducting your MLB betting analysis.

Streaky Giants Looking to Start Another Run

The San Francisco Giants have had two winning streaks of five games, another of six games and a losing streak of five games in the past month-plus.

They had a more modest two-game run going before falling 5-3 in the finale in Colorado on Wednesday. That result aside, the San Francisco offense has been humming of late, producing at least six runs in eight of its previous 10 games

Only the mighty Dodgers score more runs per game than the Giants (5.1). They were done in Wednesday by going 1-for-10 with runners in scoring position and leaving eight runners on, but that was an aberration for a team that hits .271 (third in the majors) with men on base.

The San Diego Padres games this weekend at Oracle Park presents an intriguing matchup between a top-notch rotation and a deep San Francisco lineup filled with professional hitters, if not any superstars.

Who’s Hot

Manny Machado, Padres 3B: Two more hits Thursday raised his National League-leading average to .355.

Taylor Rogers, Padres RP: Picked up save No. 15 (tops in the majors) to finish off the series in Philadelphia and has allowed only one run on the season.

Thairo Estrada, Giants 2B: Went 7-for-11 with two doubles and two walks in the trip to Colorado

Mike Yastrzemski, Giants OF: Batting .313 with a pair of homers in 14 games since returning from COVID.

Who’s Not

Trent Grisham, Padres CF: His average has been below .200 since April 9 and he hasn’t homered since April 16.

Jurickson Profar, Padres LF: His average has been below .200 since April 29 and he hasn’t homered since April 27.

Evan Longoria, Giants 3B: He’s played in only seven games since returning from finger surgery and it’s been a bit of a slog – he’s 4-for-23 with no walks and eight strikeouts.

Jose Alvarez, Giants RP: Served up the go-ahead homer Thursday and has been charged with four runs in 2⅓ innings over his last four appearances.

Injury Update

Padres SS Fernando Tatis Jr. remains in rehab from a fractured wrist. He is only throwing balls, not catching them, and has yet to swing a bat. Tatis is eligible to return from the IL in June. One would think that injuries on this level would move the meter on Padres vs Giants series odds, but does it?

Also targeting a June return for San Diego is outfielder Matt Beaty, who injured his shoulder in a dive, on May 7.

High-leverage lefty reliever Tim Hill (shoulder) is playing catch and will be re-evaluated upon the team’s return to San Diego on Monday.

The Giants have a lefty reliever of their own nearing a return in Jake McGee (back). He is eligible to come off the IL next week.

Rangers vs Astros Series Odds Betting Tips

On paper, this is the best series in baseball this weekend. It pits two of the top teams in the National League, one surviving on its pitching and the other largely on its offense. It makes betting on the series a bit of a challenge, as games will be tight — 12 of their 19 matchups in 2021 were decided by three runs or fewer, an incredible seven – by one run.

With six solid pitchers lined up as starters, perhaps one simple strategy is to lean toward the run line and take the underdog in each game.

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