San Francisco 49ers vs Arizona Cardinals

NFL Week 11’s Monday Night Football comes to you from Glendale, Arizona, as the San Francisco 49’ers make a trip to their NFC West divisional rivals, the Arizona Cardinals. This is the next big test for the 49’ers, whose road performances in 2021 earned them a Wild Card slot in the postseason. But they are up against a Cardinals team that’s keen to improve on a disappointing 3-5 home record last year.

Team Scores and Stats

Team Ranked Stats (2022-2023)

Team Leaders


49ers vs Cardinals Highlights

The 49’ers lead this tightly-contested series by 32-39 going into the 2022 season, but recent fortune has fallen in favor of Kliff Kingsbury’s Cardinals, who have taken victory in 7 of the last 10 encounters between these two old-time foes. True to the Cardinals form last year, they seem to struggle more in their home fixtures than they do on the road, with 2 of the 49’ers 3 victories in the last 10 coming in front of the Arizona home crowd.

Statistically, the 9’ers were the better side on offense and defense last season during the regular season, yet finished beneath the Cardinals for the second year running. They will be keen to correct that this year, and there is no better time for that than the present.

Now it’s time to prepare for the 49’ers vs Cardinals matchup. Should you decide to bet on NFL games and place some money down, we advise backing the Cardinals to pick up a home victory, although we would expect this one to be a closely-fought duel. Expect the Cardinals’ offense to pick up more points through the air than on the ground in this game, with the 49’ers defense averaging 403 yards per game on the run all season last year. If there are no injuries, that is. Among the best tips we can give you for taking on any wagering action is to check out the NFL injury report before any NFL schedule game.

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