San Francisco 49ers vs Denver Broncos

Week 3 sees a rematch of Super Bowl 24 in an NFC West vs AFC West battle. The 49ers vs Broncos sees San Fran travel to Mile High to try and get a win over their old divisional foe Russell Wilson. Who will the NFL betting odds make the favorite for this one?

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Team Ranked Stats (2022-2023)

Team Leaders


Packers vs Buccaneers Highlights

The San Francisco 49ers are taking a leap into the unknown in 2022, riding with Trey Lance under center and seeking to jettison Jimmy Garoppolo. All this despite reaching the NFC championship under Jimmy G last time round. They have done what they can to support Lance, securing star wideout and offensive chess piece Deebo Samuel to a new contract in the off-season. If Shanahan is the offensive mastermind, Lance will have a good chance to be a solid NFL starter in his first season as a leader.

The Denver Broncos haven’t made the playoffs since they won Super Bowl 50 at the end of the 2015 season. Such a run of mediocrity will not be accepted, and their trade for star quarterback Russell Wilson is evidence of this. All their eggs are in the Wilson basket, and head coach Nathaniel Hackett will relish having him in his offense. Can they break their playoff drought this season?

Although they are two of the oldest teams in the league, these two rarely face off against each other, as they come from different conferences. San Fran has the edge 8-7, including that 55-10 Super Bowl beat-down in 1990. They also won the last meeting in 2018 by a score of 20-14.

If you’re betting on NFL games in Week 3, how should you play this one? Broncos should have enough to cover the spread, but not by much. Expect Denver to take care of business at home in a close and tense affair.

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