Diamondbacks’ Bats Look to Stay Hot Against Rival Giants
D'Backs vs Giants Betting Odds: San Francisco -135 Series Favorites
Thursday is a relatively light day across Major League baseball, with only five games on today’s MLB schedule. The abbreviated slate culminates at 9:45 p.m. ET with the Arizona Diamondbacks opening a four-game series against the National League West rival San Francisco Giants at Oracle Park.
San Francisco is a -1.5 (+140) favorite on the run line and -155 on the moneyline, with Arizona +1.5 (-166) on the spread and +130 to win outright.
The projected total is 8, with a slight lean to the Under at -118 odds. The Giants are also -135 favorites to win the series, compared to +105 for the Diamondbacks.
What should bettors expect? Read on as we break down both MLB teams and assess the D’Backs vs Giants betting odds in our MLB series preview.
D’Backs vs Giants Game 1
D’Backs vs Giants 
Day/Time:
Location: Oracle Park, San Francisco, California
Streaming: FS1
D’Backs vs Giants Betting Trends
The Arizona Diamondbacks are 10-9 against the run line, but just 3-7 over their last 10 games. Arizona’s games have trended slightly toward the Under, as the Diamondbacks are 9-10 against the Over/Under.
Meanwhile, the San Francisco Giants are 8-11 ATS, including just 4-6 over their last 10. As for the Over/Under, the Giants are 11-8.
It’s important to remember these betting trends when assessing the D’Backs vs Giants betting odds.
Hot Bats in the Desert
The Diamondbacks are off to an up-and-down start on the heels of last season’s World Series appearance, opening 9-10. They are coming off a 5-3 loss to the Cubs on Wednesday, which marked the end of a 3-3 homestand.
Oddsmakers have reasonably high expectations for the Diamondbacks, projecting them for 84.5 regular-season wins. The Diamondbacks are also +1800 to defend their National League pennant and +4000 to win the World Series, one of 14 clubs with 40/1 or better MLB betting odds.
Second baseman Ketel Marte has gotten off to a raging start, batting .325 with five homers and a .977 OPS over his first 77 at-bats. Similarly, left fielder Lourdes Gurriel Jr. has five homers and 20 RBI. The Diamondbacks are tied for third in MLB in runs scored (106) and eighth in home runs (22).
Theoretically, the Diamondbacks should continue to improve as their pitching rounds into form. Jordan Montgomery is expected to make his Arizona debut on Friday, giving them another trusted veteran behind staff ace Zac Gallen.
Arizona’s plus-19 run differential leads the NL West and is third-best in the league behind Atlanta (plus-29) and Milwaukee (plus-25). Be sure to keep that in mind when analyzing the D’Backs vs Giants betting odds.
Waiting Game for Slow-Starting Giants
The Giants have struggled out of the gate, starting 8-11. They are coming off a 3-1 victory over Miami on Wednesday, which completed a six-game road trip.
Oddsmakers are still a bit leery of the Giants, projecting them for 83.5 regular-season wins. The Giants are also +3500 to win the NL and +7500 to win the World Series. Only nine MLB teams currently have longer World Series odds.
The Giants’ revamped lineup hasn’t produced much, averaging only 4.1 runs over their first 19 games. Altogether, they rank 19th in runs (79), 18th in home runs (17) and 17th in OPS (.696).
San Francisco invested big money this offseason in third baseman Matt Chapman, designated hitter Jorge Soler and center fielder Jung Hoo Lee, a heralded free agent from Japan, but all three have gotten off to slow starts at the plate.
Outfielder Michael Conforto (.292 average, four HR, .897 OPS) is San Francisco’s most productive hitter at the moment.
Like Arizona, San Francisco bolstered its rotation late in spring training with the addition of Blake Snell. The reigning NL Cy Young winner has been hit hard over his first two starts, but positive regression is expected as his ramp-up continues.
Despite their offensive struggles, the Giants have gone Over the total in 11 of their first 19 MLB games or at a rate of 57.9%. That’s among the highest in MLB.
Series Probables
âš¾ Game 1 âš¾
Thursday, 9:45 p.m. ET
Ryne Nelson vs Logan Webb
Nelson was sharp his last time out, allowing just one run over six innings in a 4-2 victory over St. Louis. He will oppose Webb, who is 1-1 with a 3.80 ERA across his first four starts. Webb, a runner-up for the NL Cy Young in 2023, has gone at least six innings in three of those appearances.
âš¾ Game 2 âš¾
Friday, 10:15 p.m. ET
Jordan Montgomery vs Blake Snell
Montgomery will make his Diamondbacks debut after signing a one-year, $25 million deal in late March. The veteran left-hander completed his latest ramp-up start for Triple-A Reno on Saturday, allowing seven runs over 3.2 innings. More importantly, he threw 71 pitches while showcasing good velocity.
His counterpart, Snell, also got off to a delayed start after waiting until late in spring training to sign. The reigning NL Cy Young winner, Snell inked a two-year, $61 million deal. Still a bit rusty, Snell has allowed 10 runs over seven innings in his first two appearances as a Giant.
âš¾ Game 3 âš¾
Saturday, 4:05 p.m. ET
Zac Gallen vs Kyle Harrison
Gallen has picked up where he left off last MLB season, going 3-0 with a sparkling 1.64 ERA across his first four starts. He has struck out 26 batters over 22 innings and has yet to allow a home run, showcasing the same elite repertoire that made him a Cy Young finalist in 2023.
The Giants will counter with Harrison, who is 2-1 with a 4.70 ERA. The 22-year-old left-hander is among baseball’s highest-rated prospects.
âš¾ Game 4 âš¾
Sunday, 4:05 p.m. ET
Merrill Kelly vs Jordan Hicks
Kelly is 2-0 with a 2.19 ERA in his first four starts. He will face Hicks, a converted reliever who is 2-0 with a 1.57 ERA in his first four appearances as a Giant. Hicks is also one of baseball’s hardest throwers, averaging 100.3 mph on his fastball last season.
For MLB game predictions, betting analysis and more, visit Point Spreads Sports Magazine.
