NFL Week 10 Full Schedule with Spreads: Betting Analysis

Fair Slate of Games on Tap For Bettors

The NFL Week 10 full schedule losses a bit of luster after last week’s amazing schedule. That doesn’t mean there aren’t some decent games and some good betting opportunities in store for Week 10. That’s all any football bettor can ask for. Below is the NFL Week 10 Full Schedule with spreads.

Panthers logo Carolina Panthers at Chicago Bears Bears logo

Day/Time:
Odds: Chicago -2
Moneyline: Chicago -125

The NFL Week 10 full schedule begins with a decent game in Chicago. Bryce Young and Justin Fields will get the spotlight here, although the two defenses will probably determine the winner of the game. The Bears have three straight NFC Central games after this one. The Panthers have the Cowboys on deck at home, so this could be a bit of a flat spot. The Bears should be the first of the NFL Week 10 winners, but it’s still hard to back them in this spot.

Colts logo Indianapolis Colts at New England Patriots Patriots logo

Day/Time:
Location: Frankfurt, Germany
Odds: New England -4
Moneyline: New England -192

The NFL Week 10 point spread in this one is New England -4. That’s likely one of the highest lines the Patriots are favored by this season. The game will be played in Frankfort, Germany, as the NFL looks to expand its hold. The Colts could have Anthony Richardson at quarterback. But they also have Gardner Minshew, so they won’t feel the need to rush Richardson. The Patriots beat the Colts 26-3 last season and are looking to get back into the playoffs, but it won’t be easy due to the competition in the AFC East.

Saints logo New Orleans Saints at Minnesota Vikings Vikings logo

Day/Time:
Odds: Minnesota -2.5
Moneyline: Minnesota -130

This is the first of two road games for the New Orleans Saints, while Minnesota returns home after two straight road games. The Saints figure to throw the ball quite a bit with Derek Carr and the Minnesota defense isn’t anything special. Minnesota can also move the ball throw the air so that this one could turn into a shootout. The NFL Week 10 over-under predictions call for a good look at the over in this one.

Packers logo Green Bay Packers at Pittsburgh Steelers Steelers logo

Day/Time:
Odds: Pittsburgh -3
Moneyline: Pittsburgh -155

The Pittsburgh Steelers find themselves as 3-point favorites over the Green Bay Packers in this game. The Steelers seem to be a better underdog than the favorite, but Pittsburgh was 4-2 last season against the spread when favored. There are a lot of questions surrounding Green Bay right now. While the Packers were fine after Brett Favre moved on, it’s doubtful Jordan Love is the next Aaron Rodgers. Pittsburgh always seems to get the most from its players, a testament to coach Mike Tomlin. The Steelers are worth considering for one of your NFL Week 10 parlay picks.

49ers logo San Francisco 49ers at Jacksonville Jaguars Jaguars logo

Day/Time:
Odds: San Francisco -1
Moneyline: San Francisco -115

This one could very well be the best game on this week’s schedule. The NFL Week 10 spread on this game is San Francisco -1. The NFL power rankings have the 49ers about 2.5 points better on a neutral field, so the line is about where it should be. Jacksonville is coming off a road game at Pittsburgh, while the 49ers are coming off their bye week. This is the type of game the Jaguars need to win to solidify themselves as contenders. But the 49ers pose a few matchup problems for Jacksonville.

Texans logo Houston Texans at Cincinnati Bengals Bengals logo

Day/Time:
Odds: Cincinnati -9.5
Moneyline: Cincinnati -440

The Bengals appear to be the most likely NFL Week 10 winners, as they’re big 9.5-point favorites over the Texans in this game. Houston will get better, but it may take a little while. The team was able to get some decent draft picks when trading Deshaun Watson and grabbing some good players. This is a potential trap game for the Bengals, who are coming off games with the 49ers and Bills with Baltimore up next. The Bengals should get the victory, but it’s tough to lay close to double-digits in this spot.

Browns logo Cleveland Browns at Baltimore Ravens Ravens logo

Day/Time:
Odds: Baltimore -3
Moneyline: Baltimore -155

The Ravens are favored by three points in this one, which might be a little on the low side. But bettors are expecting better things from the Cleveland Browns this season after having Watson for a full training camp. Still, the Ravens have to be considered the better team going into the season and should be ahead in the NFL Week 10 standings. The two teams split last year’s games, with each winning at home. This may not be one of the best NFL betting opportunities this week, but it’s easier to make a case for the Ravens in this one.

Titans logo Tennessee Titans at Tampa Bay Buccaneers Buccaneers logo

Day/Time:
Odds: Tennessee -1
Moneyline: Tennessee -115

You know things are bad when you’re a home underdog to the Tennessee Titans, but that’s where the Buccaneers find themselves this week. Yes, it’s a huge drop-off from Tom Brady to Baker Mayfield or Kyle Trask, but the Bucs did manage to win enough to get into the playoffs last season. The Titans won’t be a road favorite often this season. There’s this game and perhaps at Houston and that’s about it unless they come out and play well. The NFL Week 10 odds in this one suggest the Bucs in a teaser to move the line to a touchdown.

Falcons logo Atlanta Falcons at Arizona Cardinals Cardinals logo

Day/Time:
Odds: Atlanta -2.5
Moneyline: Atlanta -142

This isn’t one of the more appealing games on the schedule this week. The Falcons are a pretty average team. But the Cardinals aren’t very good and could be in for a long season, especially if Kyler Murray missed much of the year. The Falcons have their bye the week after this game and will be trying to post an impressive win to get an extra day or two off. Arizona could very well be underdogs in every game this season and for good reason. Look to Atlanta as one of your NFL Week 10 NFL picks.

Lions logo Detroit Lions at Los Angeles Chargers Chargers logo

Day/Time:
Odds: Los Angeles -3
Moneyline: Los Angeles -162

This has the potential to be a pretty solid game if the Lions are playing up to expectations. Detroit is the favorite in the NFC North and coming off its bye week, so this isn’t a bad spot for them. The Chargers are playoff contenders again, but with the Chiefs in the same division, a wild-card berth is most likely. Los Angeles is coming off a Monday night game with the Jets, so it’s a short week for them. This is one of the best NFL Week 10 matchups on the schedule, but a tough game to bet right now.

Commanders logo Washington Commanders at Seattle Seahawks Seahawks logo

Day/Time:
Odds: Seattle -4
Moneyline: Seattle -192

The Seattle Seahawks find themselves as 4-point favorites over the Commanders. The moneyline is a shade higher than you normally find with a 4-point favorite. Seattle lost a little bit of its home magic last season, going 5-4 straight-up and 4-5 against the spread. Washington isn’t a bad football team, but do have the Giants and Cowboys on deck. The Commanders have the ability to play teams close and are worth a look as one of your NFL Week 10 spread picks in this game.

Giants logo New York Giants at Dallas Cowboys Cowboys logo

Day/Time:
Odds: Dallas -5.5
Moneyline: Dallas -225

Longtime rivals New York and Dallas get together once again. Games between these two teams are usually entertaining. Dallas returns home after playing at Philadelphia, while the Giants are coming off a game with the Raiders. The Giants weren’t quite as good as they looked last season and that may show here. A lot of it has to do with Dallas being able to put last week behind it and concentrate on the Giants. The Cowboys won both games between the two last year. The NFL Week 10 betting odds of Dallas -5.5 are reasonable.

Jets logo New York Jets at Las Vegas Raiders Raiders logo

Day/Time:
Odds: New York -2.5
Moneyline: New York -135

This game could be a decent one, depending on how Jimmy Garoppolo is playing for Las Vegas. He’s seen as more of a system quarterback by some. But that didn’t stop the Raiders from going out and getting him. The NFL Week 10 spreads have the Jets favored by 2.5 and New York has a rematch with Buffalo up next. The Raiders could be worth a look in a teaser, allowing bettors to move the line to +8.5.

Broncos logo Denver Broncos at Buffalo Bills Bills logo

Day/Time:
Odds: Buffalo -6
Moneyline: Buffalo -250

The NFL Week 10 full schedule wraps up with the Denver Broncos visiting Buffalo for the Monday night game. The Buffalo Bills standings should see Buffalo leading the AFC East. How Denver fares with a new coach remains to be seen, but the team can’t be any worse than it was a year ago. Buffalo is coming off a game with Cincinnati and has the Jets up next. There could be a little bit of a letdown here, although playing on Monday night could cut that down. Denver is coming off a game with the Chiefs. Both teams are coming off of big games, making it hard to use this game for one of your NFL Week 10 spread picks.

For NFL betting news, odds analysis, and more, visit Point Spreads Sports Magazine.

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