NFL Week 12 Full Schedule with Spreads: Kicks Off With Bears vs Lions

The NFL Week 12 full schedule brings with it the traditional Thanksgiving feast of NFL games, with three games on tap. The Detroit Lions and Dallas Cowboys host their traditional holiday games, with the 49ers making a trip to Seattle for the final game of the day. Below is the NFL Week 12 Full Schedule with spreads.

Overall, the slate isn’t bad. There are a few big games on the schedule, along with a few that will only be watched by diehard fans and those who partake in NFL betting.

The NFL Week 12 full schedule kicks off with an NFC North showdown between the Green Bay Packers and the Detroit Lions. This is a rematch of the Week 4 game that was played in Green Bay. The Lions were 4-1 straight-up and ATS as home favorites last season. The Packers were 3-2 as an away underdog last season and 1-4 in totals in those games. The NFL Week 12 lines appear to be pretty much where they should be, but Green Bay’s under tendency suggests that could be the way to get your Thanksgiving Day’s betting activities off to a start.

This is the first meeting of the year between these two longtime rivals. The teams meet again in the final week of the season. The Cowboys are favored by 6 against Washington in what could be a decent game. Dallas was solid as a home favorite last year, going 7-0 straight-up and 5-2 against the spread, while the Commanders were 2-3 as an away underdog. The Cowboys are the largest of the NFL Week 12 favorites this week.

A key three-game stretch for San Francisco, which visits Philadelphia next week and then returns home for the rematch with Seattle. The 49ers won both meetings last year and were 4-3 on the season as a home favorite straight-up. San Francisco went 3-4 against the spread. The Seahawks have tailed off at home the last few seasons. Seattle is just 8-9 straight-up at home the past two seasons after going 17-8 the three prior seasons. Six of those nine losses were by six points or less. Seattle should be one of your NFL Week 12 bets in a teaser, allowing you to push the line to Seattle +7.5.

The first-ever Black Friday NFL game will take place, as the New York Jets host the Miami Dolphins in a key AFC East contest. The game will give guys something to bet on while their wives are out doing some holiday shopping, so it’s a win-win situation for all. This is the first meeting of the year between these two, who will meet again on Dec. 17. The NFL Week 12 betting lines have the Jets as 2.5-point favorites, which could be a little bit high. The Dolphins were 4-2 against the spread as an away underdog last year despite going just 1-5 straight up. Miami lost by three points twice and by two points on one occasion, so they played tough. The Jets were just 1-2 as a home favorite and 2-6 in totals at home. But that was before Aaron Rodgers.

The NFL Week 12 full schedule gets going Sunday with a bit of a lackluster game between the Colts and Tampa Bay. The Colts should have the quarterback edge here with either Anthony Richardson or Gardner Minshew. Indianapolis is coming off its bye week, while the Buccaneers were at San Francisco the previous week. Indianapolis was just 2-6 straight-up at home last season. This could be one of your NFL week 12 over under picks on the under.

New Orleans is coming off its bye week and playing the Falcons for the first time this season. The teams meet again in the final game of the regular season. The Saints won both meetings last year by a total of four points. It was one of just three home losses the Falcons suffered last year. All three losses were by three points or less, so this is probably a decent game to use in your NFL Week 12 parlay picks or teaser picks.

The Jaguars are favored by 4.5 points on the road, something that happened just once last year. Jacksonville traveled to Houston as 3.5-point favorites and won 31-3 in Week 17. But Houston did win the earlier game which was played in Jacksonville. These two met in Week 3. The Jaguars do have a tough game against the Bengals up next, so this isn’t the greatest of spots for them. But being a division rival, Jacksonville should be motivated for this game, especially after losing to Houston at home last season. It’s not the most exciting of the NFL Week 12 matchups but it is an interesting game from a betting perspective.

The Panthers are coming off a game with Dallas and now visit Tennessee, who just wrapped up three straight road games. The Titans are favored by a single point. Bryce Young should have some of the rookie mistakes corrected. But at this point in his career, it’s hard to say he’s much better than Ryan Tannehill. He will be a better quarterback when it’s all said and done, but rookie QBs are going to struggle at times. The Titans aren’t world-beaters, but they are a veteran team that could be a little better than the Panthers this season. It may not be a popular play by going against Young, but the Titans deserve a look as one of your NFL Week 12 ATS picks.

This isn’t a bad matchup, as the Patriots visit the Giants. The NFL Week 12 spread of New York -1.5 lets you know the sportsbook isn’t entirely sold on New York despite the Giants making the playoffs last season. The Patriots could be a little better than people are expecting, but the AFC East is going to be tough this season. The Giants were 3-2 as a home favorite last season, while New England was 3-3 as an away underdog and 5-1 in totals when an away underdog. With New York going 3-2 in totals as a home favorite last year, the over could be worth a look in this spot.

The Bengals are favored by 4.5 points over the Steelers in what’s the first meeting of the year between the two teams. The rematch will take place in Week 16. The teams split their two games last season and both were close contests. The Bengals are coming off a road game at Baltimore, while the Steelers were at Cleveland last week. This is the type of game the Steelers need to slow down and not try to match the Bengals point-for-point on the scoreboard. Pittsburgh has a better shot in a 21-17 type of game than in a 35-31 game. The Steelers deserve a look as one of your NFL Week 12 spread picks.

The Sunday late games start off with a fair matchup between the Cleveland Browns and Denver Broncos. There is a bit of pressure on both quarterbacks, who are paid quite well to deliver results. Cleveland is coming off games with the Ravens and Steelers. Despite Denver’s problems in 2022, the Broncos were still 4-4 at home. Sean Payton should be able to get more out of Russell Wilson than we saw last season, which should be evident in the NFL box scores. The price on Denver is cheap and the Broncos should be considered for one of your NFL Week 12 picks against the spread.

The Los Angeles Rams are small favorites on the road in a game that’s a rematch of their Week 6 contest. The two teams split their games last season. If healthy, the Rams are going to be a little better than they’re getting credit for. The Cardinals are likely in for a long season and how they start could determine whether or not Kyler Murray plays at all this season. This is one of the least appealing of the NFL Week 12 games and a tough one to wager on.

The Kansas City Chiefs are trying to make it in back-to-back NFL championship games, but these are the types of games the Chiefs have sometimes had trouble with. Kansas City is coming off its big rematch with the Eagles and now has a division foe waiting in the wings. The Chiefs won both games against the Raiders last year, winning by one and then 31-13. This is the first meeting between the teams this season. Las Vegas will be hopping for this game. The NFL Week 12 Vegas odds of Kansas City -5 might be a shade high here considering the situation Kansas City is in.

Another tough game for the Eagles, who are coming off the Cowboys and Chiefs and have the 49ers and Dallas on tap. This one is a bit tough to try and handicap without knowing the results of the Eagles and the Chiefs. If Philadelphia pulled the Week 11 upset, you have to look at the Bills as one of your NFL Week 12 upsets, as there will be a definite letdown. The Bills have a tough game prior to this one, as well, against the New York Jets.

The Sunday night game is a pretty good one, as the Ravens travel across the country to face the Los Angeles Chargers. Baltimore is coming off division games against the Browns and Bengals, while the Chargers are in a decent spot schedule-wise. Los Angeles was 3-3 as a home favorite last season, but Baltimore was 4-1 as an away underdog. The teams have different styles and the NFL Week 12 spreads look about right in this one.

The NFL Week 12 full schedule wraps up the week with an NFC North battle between the Bears and the Vikings. The teams met in Week 6 and Minnesota won both meetings last year. The Bears are moving in the right direction. It’s a question of how long it’s going to take Chicago to get there. The Vikings are expected to take a step backward, but they’re almost to the point of being underrated a little bit now. It’s still a team that can battle for a playoff spot. Minnesota should be ahead of Chicago in the NFL Week 12 standings and should be able to get the win here.

For more NFL results, odds, and analysis visit Point Spreads Sports Magazine.

Can’t get enough? Here’s more!

• NFL Week 11 Full Schedule
• Las Vegas Raiders 2023 Future Odds
• Green Bay Packers 2023 Future Odds
• Sam Hubbard’s Stats: Bengals Lineman Will Continue To Be an X-Factor
• NFL Preseason Week 2 Odds